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Table 44.2

Drug Therapy of Bradycardia

DrugCommentDose (IV)
AtropineInhibition of vagal toneBolus of 500–1000μgm, with further doses at 5 min intervals up to a total dose of 3 mg to achieve target heart rate
DobutamineCardiac beta-1 receptor stimulationStart infusion at 10μgm/kg/min
High doses may provoke ventricular arrhythmiasAdjust rate of infusion to achieve target heart rate
GlucagonTo reverse beta blockadeBolus of 2–10 mg followed by infusion of 50μgm/kg/h