Target (and Range) International Normalized Ratio (INR) for Mechanical Prostheses
Prosthesis thrombogenicity | No patient risk factors* | >1 risk factor* |
---|---|---|
Low | 2.5 (2.03.0) | 3.0 (2.53.5) |
Medium | 3.0 (2.53.5) | 3.5 (3.04.0) |
High | 3.5 (3.04.0 | 4.0 (3.54.5) |
Prosthesis thrombogenicity:
|
* Patient-related risk factors: mitral or tricuspid valve replacement; previous thromboembolism; atrial fibrillation; mitral stenosis of any degree; left ventricular ejection fraction <35%.
** The OnX aortic valve has recently received a licence for an INR target 1.8 and range 1.52.0.