Initial Antibiotic Therapy for Suspected Septic Arthritis
| Organisms on Gram stain | Antibiotic therapy (IV, high dose) | |
|---|---|---|
| Not allergic to penicillin | Penicillin allergy | |
| Gram-positive cocci | Flucloxacillin | Clindamycin |
| Gram-negative cocci (gonococci) | Ceftriaxone | Minor allergy: ceftriaxone |
| Major allergy: meropenem | ||
| Gram-negative rods | Ciprofloxacin + gentamicin | Ciprofloxacin and gentamicin |
| None seen: gonococcal infection unlikely | Flucoxacillin | Clindamycin |
| None seen: gonococcal infection likely | Ceftriaxone | Minor allergy: ceftriaxone |
| Major allergy: meropenem | ||