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Table 73.2

Focused Assessment in Acute Upper GI Bleeding

History
Has there been haematemesis, melaena or both? Did vomiting precede the first haematemesis (suggesting Mallory-Weiss tear, although this history is absent in 50% of cases)? Was bleeding associated with syncope?
Has there been previous upper gastrointestinal bleeding? What was the cause?
Current and recent drug therapy: ask specifically about non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, clopidogrel, warfarin and direct-acting oral anticoagulants (fondaparinux, rivaroxaban, apixaban, dabigatran)
Usual and recent alcohol intake
Known chronic liver disease
Other medical problems, for example heart disease, chronic kidney disease, haematological conditions.
Examination
Estimate the volume of blood loss from the physiological observations:
Major bleed (>1500 mL; >30% of blood volume)Minor bleed (750 mL; <15% of blood volume)

Pulse 120/min

Systolic BP <120 mmHg (note this is influenced by age and usual blood pressure)

Cool or cold extremities

Tachypnoea (respiratory rate >20/min)

Abnormal mental state: agitation, confusion, reduced conscious level

Pulse <100/min

Systolic BP 120 mmHg, with postural fall <20 from lying to sitting

Normal perfusion of extremities

Normal respiratory rate

Normal mental state

Signs of chronic liver disease?

Abdominal tenderness or masses?

Hepatomegaly, splenomegaly or ascites?