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Table 42.3

Intravenous Therapy to Terminate Supraventricular Tachycardia (AV Nodal Re-Entrant Tachycardia and AV Re-Entrant Tachycardia)

DrugCommentDose

Adenosine

Verapamil

Esmolol

Metoprolol

May cause facial flushing, chest pain, hypotension, bronchospasm

May cause brief asystole, atrial fibrillation and non-sustained ventricular tachycardia

Use with caution in patients with severe airways disease

Contraindicated in patients with heart transplant

May cause hypotension Contraindicated in patients taking beta blockers or in heart failure

Short-acting (half-life 8 min) beta-1 selective beta blocker

May cause hypotension

6 mg IV bolus through large bore cannula, followed by rapid saline flush. Repeat as necessary, if no response within 2 min, with 12, 18 and 24 mg boluses

5 mg IV over 5 min, to maximum dose of 15 mg

500μgm/kg over 1 min, followed by 200μgm/kg over 4 min

5 mg IV over 5 min, to maximum dose of 15 mg