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Table 110.3

Management of Breathlessness

Non-pharmacological measures

Sit the patient up (increases vital capacity and reduces abdominal splinting)

Arrange cool airflow over the patient's face with a fan or by opening a window

Maintain a calm empathic approach and presence

Reassurance

Physiotherapy

Breathing/relaxation exercises

Activity pacing

Complementary therapies

Pharmacological therapy
OxygenMay be helpful if patient is hypoxic (i.e. arterial SaO2<92%)
Beta-2 agonistsGive salbutamol by inhaler or nebuliser if there is bronchospasm.
Opioids

Start with oral morphine 1 mg as required, if tolerated and beneficial then consider using this regularly every 4 hrs and as required.

After 2 days: calculate the total dose given over 24hrs, and use this to recalculate the 4-hourly dose (the new 4-hourly and ‘as required’ dose is one-sixth of the new total daily dose).

Once a stable dose has been reached, this can be converted to once- or twice-daily modified-release morphine.

If the patient is already on regular (analgesic) morphine: increase the dose of regular morphine by 30–50% every 2–3 days until symptoms are controlled, or adverse effects prevent further dose increases.

Anxiolytics

If anxiety-related breathlessness, consider use of long-term anxiolytic (e.g. citalopram).

For panic-related breathlessness in patient approaching end of life then consider use of low dose lorazepam (0.5 mg to 1 mg up to 12-hourly).