Antiemetic Therapy
| Drug | Receptors | Indications | |
|---|---|---|---|
| Cyclizine | H1/Muscarinic-ACh | Raised intracranial pressure Motion sickness Inoperable bowel |  |
– central and peripheral action – peripheral action only | D2/5HT4 | Gastric stasis Gastric irritation Inoperable bowel obstruction if no colic |  |
| Haloperidol | D2 | Opioid induced Metabolic causes Inoperable bowel obstruction |  |
| Ondansetron | 5HT3 | Chemo/RT Gastric irritation |  |
butylbromide | Muscarinic-ACh | Inoperable bowel obstruction with colic |  |
| Levomepromazine | D2/H1/ Muscarinic-ACh | Broad-spectrum antiemetic, often third-line use |  |
RT, radiotherapy.