Specific Antidotes. NB: Discuss the Case with a Poisons Centre First, Unless You are Familiar with the Poison and its Antidote, As Some Antidotes May Be Harmful if Given Inappropriately
| Poison | Antidote |
|---|---|
| Anticholinergic agents | Physostigmine |
| Arsenic | Dimercaprol |
| Benzodiazepines | Flumazenil |
| Beta-blockers | Glucagon |
| Calcium antagonists | Calcium gluconate |
| Cyanide | Dicobalt edetate alone or sodium nitrite + sodium thiosulphate |
| Dabigatrin | Idarucizumab |
| Digoxin | Digoxin-specific antibody fragments |
| Ethylene glycol | Ethanol or 4-methylpyrazole |
| Fluoride | Calcium gluconate |
| Buproprion, local anaesthetics | Lipid emulsion (Intralipid®) |
| Iron | Desferrioxamine |
| Lead | Dimercaprol or penicillamine |
| Mercury | Dimercaprol or penicillamine |
| Methanol | Ethanol or 4-methylpyrazole |
| Opioids | Naloxone |
| Organophosphates | Atropine |
| Paracetamol | Acetylcysteine (Appendix 36.1) |
| Thallium | Berlin blue |
| Warfarin | Vitamin K or fresh frozen plasma or prothrombin complex concentrate |
| (see p. 591) |