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Table 36.5

Specific Antidotes. NB: Discuss the Case with a Poisons Centre First, Unless You are Familiar with the Poison and its Antidote, As Some Antidotes May Be Harmful if Given Inappropriately

PoisonAntidote
Anticholinergic agentsPhysostigmine
ArsenicDimercaprol
BenzodiazepinesFlumazenil
Beta-blockersGlucagon
Calcium antagonistsCalcium gluconate
CyanideDicobalt edetate alone or sodium nitrite + sodium thiosulphate
DabigatrinIdarucizumab
DigoxinDigoxin-specific antibody fragments
Ethylene glycolEthanol or 4-methylpyrazole
FluorideCalcium gluconate
Buproprion, local anaestheticsLipid emulsion (Intralipid®)
IronDesferrioxamine
LeadDimercaprol or penicillamine
MercuryDimercaprol or penicillamine
MethanolEthanol or 4-methylpyrazole
OpioidsNaloxone
OrganophosphatesAtropine
ParacetamolAcetylcysteine (Appendix 36.1)
ThalliumBerlin blue
WarfarinVitamin K or fresh frozen plasma or prothrombin complex concentrate
(see p. 591)