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Table 25.5

Criteria for Initiation of Renal Replacement Therapy in Acute Kidney Injury

  • Anuria (no or negligible urine output for >6h)
  • Severe oliguria (urine output <200 mL over 12h) and fluid overload
  • Hyperkalaemia (potassium concentration >6.5 mmol/L) and not responding to medical treatment
  • Severe metabolic acidosis (pH <7.2 despite normal or low partial pressure of carbon dioxide in arterial blood) not responding to supportive treatment
  • Volume-overload (especially pulmonary oedema unresponsive to diuretics)
  • Severe uraemia (serum urea concentration >30 mmol/L) or specific complications of uraemia (e.g. encephalopathy, pericarditis, neuropathy)
  • AKI due to dialyzable toxins/drugs