Sepsis

Metastatic cancer

Acidosis

Corticosteroid therapy

Smoking

Trauma, surgery, burn

Myeloproliferative disorders

Neutropenia

(see Chapter102)

Myelosuppressive chemotherapeutic agents

Idiosyncratic reaction to drug (e.g. carbimazole)

Infections (e.g. viral, severe bacterial, HIV)

B12 and folate deficiency

Systemic lupus erythematosus

Felty syndrome

Haematological disorders (e.g. leukaemia)

Ethnic neutropenia (Afro-Caribbean origin is often associated with neutrophilis as low as 0.8×10⁹/L

Infections (e.g. infectious mononucleosis)

Lymphoproliferative disorders (e.g. chronic lymphocytic leukaemia, lymphoma)

Infections (e.g. viral, HIV, severe bacterial)

Immunosuppressive therapy

Systemic lupus erythematosus

Alcohol excess

Chronic renal failure

Lymphoma

Infections

Myeloproliferative disorders (e.g. chronic myelomonocytic leukaemia)

Metastatic cancer

Drug allergy

Parasitic infestation

Haematological disorders (e.g. lymphoma, leukaemia, hypereosinophilic syndrome)

Churg-Strauss vasculitis

Disorders with eosinophilic involvement of specific organs

Adrenal insufficiency (see Chapter 90)

Atheroembolism