Paracetamol Poisoning: Indications of Severe Hepatotoxicity
Rapid development of grade 2 encephalopathy (confused but able to answer questions) Prothrombin time >20s at 24h, >45s at 48h or >50s at 72h Increasing plasma bilirubin Increasing plasma creatinine Falling plasma phosphate Arterial pH <7.3 more than 24h after ingestion |