Adult Dosing

Topical ocular vasoconstrictor

• Instill 1-2 drops in the conjunctival sac(s) q3-4 hrs PRN

Pediatric Dosing

• Safety and effectiveness in pediatric patients have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Indicated for use as a topical ocular vasoconstrictor

• Hypersensitivity to any of the ingredients of the product
• Angle-closure glaucoma
• Concurrent use or use within 14 days of discontinuing MAO inhibitors

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

See Supplemental Patient Information

• Patients receiving MAO inhibitors may experience a severe hypertensive crisis when a sympathomimetic drug is given. In children, especially infants, this may lead to CNS depression causing coma and significant reduction in body temperature
• If relief is not obtained within 48 hrs of therapy, discontinue the drug and consult a physician
• Do not touch the eyelids or surrounding areas with the dropper tip as this could contaminate the medication and result in serious ocular infections

Cautions: Use cautiously in

• Hypertension
• CV disease
• Hyperglycemia (diabetes)
• Hyperthyroidism
• Infection or injury

Supplemental Patient Information

• Advise patients to discontinue the drug and promptly consult a physician if irritation, redness or blurring persists or increases, or if symptoms of systemic absorption occur (e.g., dizziness, headache, drowsiness, reduced body temperature)

Pregnancy Category:C

Breastfeeding: Safety unknown. Manufacturer advices caution.

• EENT: Mydriasis, increased redness, irritation, discomfort, blurring, punctate keratitis, lacrimation, increased IOP
• CNS: Dizziness, headache, nervousness, drowsiness, weakness, CNS depression (patients <6 yrs)
• CV: Hypertension, cardiac irregularities
• GI: Nausea
• ENDO: Hyperglycemia
• DERM: Sweating

• Ophthalmic decongestant (sympathomimetic); reduces ocular congestion and redness by stimulating alpha adrenergic receptors
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• AK-Con
• Albalon
• All Clear
• Clear Eyes
• Naphcon
• All Clear AR

US Availability

naphazoline (generic)

• OPTH SOLN: 0.1%

AK-Con, Albalon (generic)

• OPTH SOLN: 0.1%

All Clear, Clear Eyes, Naphcon

• OPTH SOLN: 0.012%

All Clear AR

• OPTH SOLN: 0.03%

Canadian Trade Name(s)

• AK-Con
• Albalon
• Clear Eyes
• Original Eye Drops
• Collyre Bleu Laiter
• Diopticon
• Naphcon Forte
• Refresh Redness Relief

Canadian Availability

AK-Con, Albalon, Naphcon Forte

• OTC OPTH DROPS: 0.1%

Clear Eyes, Original Eye Drops

• OTC OPTH DROPS: 0.12%

Collyre Bleu Laiter

• OTC OPTH DROPS: 0.5 mg/mL

Diopticon

• OTC OPTH LIQ: 0.1%

Refresh Redness Relief

• OTC OPTH SOLN: 0.1%

UK Trade Name(s)

• Murine irritation & redness relief

UK Availability

Murine irritation & redness relief

• OPTH SOLN: 0.012%

Australian Trade Name(s)

• Albalon
• Murine Clear Eyes
• Naphcon Forte

Australian Availability

Albalon, Naphcon Forte

• OPTH DROPS: 0.1%

Murine Clear Eyes

• OPTH SOLN: 0.012 mg/mL

[Outline]

Ophthalmic

Ophthalmic Decongestants

Alpha Adrenergic Agonists