Adult Dosing

Nasal congestion

• 2-3 sprays/nostril q10-12 hrs
• Max: 2 doses/24 hrs

Pediatric Dosing

Nasal congestion

• Dristan Nasal Spray
• >12 yrs: 2-3 sprays/nostril q10-12 hrs; Max: 2 doses/24 hrs

• Afrin, Afrin All Night, Afrin Extra Moisturizing, Afrin Severe Congestion, Afrin Sinus, Vicks Sine
• >6 yrs: 2-3 sprays/nostril q10-12 hrs; Max: 2 doses/24 hrs
• 2-6 yrs: ask a doctor
• <2 yrs: do not use

[Outline]

• Adult Dosing
• Pediatric Dosing

• Temporarily relief nasal congestion due to a cold, hay fever or other upper respiratory allergies

• Hypersensitivity to any of the ingredients of the product
• Concomitant use of monoamine oxidase inhibitor (MAOI) or within 2 wks of stopping MAOI

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Frequent or prolonged use of oxymetazoline nasal spray can cause recurrence of nasal congestion or worsen it
• Temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge has been reported with the treatment

Cautions: Use cautiously in

• Cardiac diseases
• Hypertension
• Thyroid disorder
• Diabetes mellitus
• Prostatic hypertrophy

Supplemental Patient Information

• Advise patients that the container to be used by one person only, as the by more than one person may spread infection

Pregnancy Category:C

Breastfeeding: Because of the local administration and limited absorption into the maternal bloodstream very little should reach the infant through breastmilk. It has been recommended over oral systemic decongestants such as pseudoephedrine during breastfeeding. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 10 June 2011).

• LOCAL: Burning, stinging, sneezing or an increase in nasal discharge, rebound congestion

• Adrenergic alpha agonist; acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa, produces constriction, resulting in decreased blood flow and decreased nasal congestion
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Afrin
• Afrin All Night
• Afrin Extra Moisturizing
• Afrin Severe Congestion
• Afrin Sinus
• Dristan
• Vicks Sinex
• Mucinex Nasal Spray
• Neo-Synephrine Severe Sinus Congestion Spray
• Sudafed OM
• Vicks Sinex VapoSpray 12 Hour

US Availability

Afrin, Afrin All Night, Afrin Extra Moisturizing, Afrin Severe Congestion, Afrin Sinus, Dristan, Vicks Sinex , Mucinex Nasal Spray, Neo-Synephrine Severe Sinus Congestion Spray, Sudafed OM, Vicks Sinex VapoSpray 12 Hour

• OTC SPRAY: 0.05%

Canadian Trade Name(s)

• Claritin Allergic Congestion Relief
• Drixoral Decongestant
• Decongestant Nasal Mist Long Lasting
• Drixoral No Drip Extra Moisturizing
• Drixoral No Drip Original
• Drixoral No Drip With Cooling Menthol
• Long Lasting Dristan Mentholated Nasal Spray
• Long Lasting Dristan Nasal Mist
• Vicks Sinex Decongestant Nasal Spray

Canadian Availability

Claritin Allergic Congestion Relief, Drixoral Decongestant

• OTC INH: 0.05%

Decongestant Nasal Mist Long Lasting, Vicks Sinex Decongestant Nasal Spray

• OTC LIQ: 0.05%

Drixoral No Drip Extra Moisturizing, Drixoral No Drip Original, Drixoral No Drip With Cooling Menthol, Long Lasting Dristan Mentholated Nasal Spray, Long Lasting Dristan Nasal Mist

• OTC SPRAY: 0.05%

Long Lasting Nasal Mist

• OTC SOLN: 0.05%

UK Trade Name(s)

• Boots Nasal Spray
• Vicks Sinex Decongestant
• Vicks Sinex Micromist
• Vicks Sinex Soother

UK Availability

Boots Nasal Spray, Vicks Sinex Decongestant, Vicks Sinex Micromist, Vicks Sinex Soother

• OTC SPRAY: 0.05%

Australian Trade Name(s)

• Chemists' Own Decongestant Nasal Spray
• Dimetapp 12 Hour Nasal Spray
• Drixine Nasal
• Logicin Rapid Relief Nasal Spray

Australian Availability

Chemists' Own Decongestant Nasal Spray, Dimetapp 12 Hour Nasal Spray, Drixine Nasal, Logicin Rapid Relief Nasal Spray

• OTC SPRAY: 0.05%

[Outline]

ENT

Nasal Preparations

Antihistamines & Decongestants

Allergy & Immunology

Nasal Preparations

Antihistamines & Decongestants