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Use and Dosing

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Severe vasomotor symptoms

estradiol

Femtrace (estradiol acetate)

Vulval and vaginal atrophy associated with the menopause

estradiol

Hypoestrogenism

estradiol

Palliative treatment of breast cancer

estradiol

Androgen-dependent prostate cancer

estradiol

Prevention of osteoporosis

estradiol

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[Outline]

Indications

Estradiol

Femtrace (estradiol acetate)

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use cautiously in

Pregnancy/Breast Feeding

Pregnancy Category:X

Breastfeeding: Limited data on the use of estradiol during breastfeeding indicates that the amount transferred into breastmilk is influenced by route of administration and dosage form. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 24 December 2010). Though this drug has found to be compatible with breastfeeding, withdrawal bleeding may occur after drug is withdrawn based upon data from AAP Policy Guidelines (available at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;108/3/776)As per manufacturer's data, estrogen administration during breastfeeding interferes with lactation by decreasing the quantity and quality of the milk. Detectable amount is secreted in breast milk; use cautiously when estradiol is administered to a nursing woman.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

estradiol (generic)

Estrace (estradiol)

Femtrace (estradiol acetate)

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Canadian Trade Name(s)

Canadian Availability

Estrace (estradiol)

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UK Trade Name(s)

UK Availability

Climaval, Progynova (estradiol valerate)

Elleste solo(estradiol hemihydrate)

Zumenon

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Australian Trade Name(s)

Australian Availability

Estrofem (estradiol hemihydrate)

Progynova (estradiol valerate)

Zumenon (estradiol)


[Outline]

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Classification

Obstetrics/Gynecology

Hormones
Estrogens

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill