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Use and Dosing

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Vulvar and vaginal atrophy associated with menopause (Estrace)

Cream

Notes:

Moderate to severe vulvar/vaginal atrophy and vasomotor symptoms associated with menopause (Estring, Femring)

Ring

Notes:

Moderate to severe symptoms of vulvar and vaginal atrophy associated with menopause (Vagifem)

Tabs

Notes:

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use cautiously in

Pregnancy/Breast Feeding

Pregnancy Category:X

Breastfeeding: Limited data on the use of estradiol during breastfeeding indicates that the amount transferred into breastmilk is significantly influenced by the route of administration and dosage forms. Vaginal administration results in measurable amounts in milk. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 18 July 2011). As per manufacturer's data, estrogen administration to nursing mothers interferes with lactation by decreasing the quantity and quality of the breast milk. Detectable amounts are secreted in breast milk, hence should not be used during lactation.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

Estrace

Estring

Femring (estradiol acetate)

Vagifem

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Canadian Trade Name(s)

Canadian Availability

Estring

Vagifem

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UK Trade Name(s)

UK Availability

Estring

Vagifem

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Australian Trade Name(s)

Australian Availability

Vagifem


[Outline]

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Classification

Endocrine/Metabolic

Sex Hormones
Estrogens

Obstetrics/Gynecology

Sex Hormones
Estrogens

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill

Drug Name: Vagifem 0.01 MG Vaginal Tablet

Ingredient(s): Estradiol

Imprint: N/A

Color(s): White

Shape: Round

Size (mm): 6.00

Score: 1

Inactive Ingredient(s): N/A

Drug Label Author:
Novo Nordisk

DEA Schedule:
Non-Scheduled


Drug Name: Vagifem 0.025 MG Vaginal Tablet

Ingredient(s): Estradiol

Imprint: N/A

Color(s): White

Shape: Round

Size (mm): 6.00

Score: 1

Inactive Ingredient(s): N/A

Drug Label Author:
Novo Nordisk

DEA Schedule:
Non-Scheduled