Adult Dosing
Acute migraine attacks (with or without aura)
- 5, 10 or 20 mg in one nostril x 1; Alt: 5 mg in each nostril x 1
- May repeat q2 hrs if headache recurs
- Max: 40 mg/24 hrs; 4 headaches in 30 days
Pediatric Dosing
- Safety and effectiveness in pediatric patients have not been established
[Outline]
- Sumatriptan should be given only if a clear diagnosis of migraine has been established
- If the patient does not respond to the first dose, reconsider diagnosis of migraine headache before administration of a second dose
- Sumatriptan is not indicated for prophylaxis of migraine or for use in the management of hemiplegic or basilar migraine
- Safety and effectiveness have not been established for cluster headache
- Sumatriptan should not be given when risk factors for ischemic, cerebrovascular, or peripheral vascular syndromes are present. Unrecognized coronary artery disease (CAD) is predicted by the presence of risk factors e.g. hypertension, hypercholesterolemia, smoking, obesity, diabetes, strong family history of CAD, female with surgical or physiological menopause, or male over 40 years of age. Do not use unless a cardiovascular evaluation establishes that the patient does not have CAD
- Serious adverse cardiac events, including acute MI, arrhythmias, and death, have been reported within a few hours following administration
- It may cause coronary vasospasm in patients with history of coronary artery disease (CAD)
- Cerebral hemorrhage, subarachnoid hemorrhage, stroke, and other cerebrovascular events have occurred with 5-HT1 agonists
- Intermittent long term users should undergo periodic cardiovascular evaluation
- Monitor BP at baseline, cardiovascular evaluation at baseline, then periodically during long-term treatment if risk factors present
Cautions: Use cautiously in
- Renal impairment
- Hepatic impairment
- Diabetes Mellitus
- Hypertension (due to possibility of unrecognized CAD)
- Cardiac risk factors
- Concomitant use with SSRI's serotonin syndrome possible
- Hx of seizure disorder
- Geriatric population (due to presence of risk factors for hypertension, hypercholesterolemia, possibility of unrecognized CAD)
Pregnancy Category:C
Breastfeeding: Safety unknown; manufacturer advises caution..
Pricing data from www.DrugStore.com in U.S.A.
- Imitrex 20 MG/ACT SOLN [Inhaler] (GLAXO SMITH KLINE)
6 act = $270.98
18 act = $790.96 - Imitrex 5 MG/ACT SOLN [Inhaler] (GLAXO SMITH KLINE)
1 act = $55.49
3 act = $136.3 - SUMAtriptan 5 MG/ACT SOLN [Inhaler] (SANDOZ)
1 act = $45.99
3 act = $125.97 - SUMAtriptan 20 MG/ACT SOLN [Inhaler] (SANDOZ)
1 act = $45.99
3 act = $119.96
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
