- After reconstitution with 1.2 mL sterile Water for Injection, administer 1 mL (0.9 mg) IM q24 hrs x2 doses
- Use with or without radioiodine imaging for follow-up of patients with well-differentiated thyroid cancer
- Indicated for IM injection to the buttock; do not administer intravenously
- Consider pretreatment with glucocorticoids in patients with local tumor expansion which may compromise vital anatomic structures (such as trachea, CNS, or extensive macroscopic lung metastases)
- For radioiodine imaging, administer radioiodine 24 hrs after the final injection of thyrotropin alfa
- Perform diagnostic scanning 48 hrs after radioiodine administration and delay post-therapy scanning additional days to allow background activity to decline
- For serum Tg testing, obtain the serum sample 72 hrs after the final thyrotropin alfa injection
Adjunctive therapy for radioiodine ablation of thyroid tissue
- After reconstitution with 1.2 mL sterile Water for Injection, administer 1 mL (0.9 mg) IM q24 hrs x2 doses
- Use after near-total or total thyroidectomy for well-differentiated thyroid cancer without metastases
- Indicated for IM injection to the buttock; do not administer intravenously
- For remnant ablation, administer radioiodine 24 hrs after the final injection of thyrotropin alfa
- Perform diagnostic scanning 48 hrs after radioiodine administration and delay post-therapy scanning additional days to allow background activity to decline
- Safety and efficacy in pediatric patients <16 yrs of age have not been established
- After reconstitution with 1.2 mL sterile Water for Injection, administer 1 mL (0.9 mg) IM q24 hrs x2 doses
- Use with or without radioiodine imaging for follow-up of patients with well-differentiated thyroid cancer
- Indicated for IM injection to the buttock; do not administer intravenously
- Consider pretreatment with glucocorticoids in patients with local tumor expansion which may compromise vital anatomic structures (such as trachea, CNS, or extensive macroscopic lung metastases)
- For radioiodine imaging, administer radioiodine 24 hrs after the final injection of thyrotropin alfa
- Perform diagnostic scanning 48 hrs after radioiodine administration and delay post-therapy scanning additional days to allow background activity to decline
- For serum Tg testing, obtain the serum sample 72 hrs after the final thyrotropin alfa injection
Adjunctive therapy for radioiodine ablation of thyroid tissue
- After reconstitution with 1.2 mL sterile Water for Injection, administer 1 mL (0.9 mg) IM q24 hrs x2 doses
- Use after near-total or total thyroidectomy for well-differentiated thyroid cancer without metastases
- Indicated for IM injection to the buttock; do not administer intravenously
- For remnant ablation, administer radioiodine 24 hrs after the final injection of thyrotropin alfa
- Perform diagnostic scanning 48 hrs after radioiodine administration and delay post-therapy scanning additional days to allow background activity to decline
