Adult Dosing
Adjuvant therapy for reduction of IOP
- 1-2 gtt in the affected eye(s) tid
Notes- Interval of about 5 minutes is needed between administration of apraclonidine and other ophthalmic preparations to prevent washout of the previous dose
- Not for injection into the eye and oral ingestion
Inhibition of perioperative IOP increases
- 1 gtt of 1% instilled in the scheduled operative eye; 1 hr before initiating anterior segment laser surgery and 2 gtt of 1% instilled upon completion of the laser surgical procedure
Pediatric Dosing
- Safety and effectiveness in pediatric patients have not been established
[Outline]
See Supplemental Patient Information
- For topical ophthalmic use only. Do not use for injection or oral ingestion
- Monitor visual fields periodically in patient using apraclonidine to delay surgery
- Closely monitor cardiovascular parameters in patients with impaired renal and hepatic function if they are receiving apraclonidine; use therapy cautiously in patients with severe, uncontrolled cardiovascular disease, hypertension, coronary insufficiency, recent myocardial infarction, cerebrovascular disease, chronic renal failure, Raynaud’s disease, or thromboangiitis obliterans
- Closely monitor the patient with depression or history of depression during treatment with apraclonidine
- Therapy may cause dizziness and somnolence, thus advise patient not to engage in hazardous activities requiring mental alertness while using apraclonidine
- Allergic like ocular reaction may develop with the use of apraclonidine; if such reactions are noted discontinue the therapy
Cautions: Use cautiously in
- Renal impairment
- Hepatic impairment
- Depression
- Thromboangitis obliterans
- Cerebrovascular disesase
- Severe cardiovascular disorder
- MI
- Uncontrolled hypertension
- Raynaud phenomenon
- Hx of vasovagal
Supplemental Patient Information
- For topical ophthalmic use only. Do not use for injection or oral ingestion
- Do not touch dropper tip to any surface
Pregnancy Category:C
Breastfeeding: Safety unknown; No information is available on the use of apraclonidine during breastfeeding. To diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 16 May 2011). Manufacturer advises caution.
Pricing data from www.DrugStore.com in U.S.A.
- Iopidine 0.5 % SOLN [Bottle] (ALCON VISION)
5 % = $114.49
15 % = $322.74 - Iopidine 1 % SOLN [Plas Cont] (ALCON VISION)
24 % = $366.26
72 % = $1035.58 - Iopidine 0.5 % SOLN [Bottle] (ALCON VISION)
10 % = $207.08
30 % = $588.57
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
