- Indicated for vaginal use only
- Tioconazole is indicated for the local treatment of uncomplicated vulvovaginal candidiasis (moniliasis)
- Therapy is contraindicated in patients who are hypersensitive to other imidazole-derivative azole antifungals
- Therapy should be used only after a physician has confirmed that the patient has a vaginal yeast infection; confirm diagnosis of vaginal candidiasis by KOH smears and or cultures
- Avoid using tampons, douches, spermicides, or other vaginal products during treatment; do not use contraceptives such as condoms and diaphragms as they may damaged and fail to prevent pregnancy or STDs
- Avoid vaginal intercourse during therapy
- Therapy may cause mild increase in vaginal burning, itching or irritation
- Safety and effectiveness in pregnant women and diabetic patients have not been established
- To avoid contamination, open applicators just prior to administration
- Advise patients to avoid use of rubber or latex products such as condoms/vaginal contraceptive diaphragms within 72 hrs following tioconazole dose
- Discontinue therapy and contact a physician if symptoms do not get better within 3 days, persist for more than 7 days, or recur within 2 months of therapy
- Discontinue use and consult a clinician if symptoms such as a rash or hives, abdominal pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge occur
- Advise patients to consult a doctor before initiating therapy if they experience lower abdominal, back or shoulder pain; fever, chills, nausea, vomiting, or foul-smelling vaginal discharge as it may indicate a more serious condition
Caution: Use cautiously in
- Recurrent vulvovaginal yeast infections
Pregnancy Category:C
Breastfeeding: Safety unknown. Vaginal tioconazole has not been studied during breastfeeding; alternate antifungal agents may be preferred, especially while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 16 June 2011.)
