Adult Dosing

Age-related decline in mental capacity, primary progressive dementia, Alzheimer's dementia, senile onset, multi-infarct dementia

• 1 mg PO tid

• Therapeutic response is usually gradual and results may not be observed until after 3-4 wks of therapy
• Place the sublingual tablet under the tongue until it dissolves completely; do not crush, chew, or swallow it whole

Pediatric Dosing

• Safety and effectiveness in pediatric patients have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Relief of signs and symptoms of age-related decline in mental capacity, primary progressive dementia, Alzheimer's dementia, senile onset, multi-infarct dementia

• Hypersensitivity to any of the ingredients of the product
• Acute or chronic psychosis

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Prior to prescribing this drug, careful diagnosis should be performed because the target symptoms are of unknown etiology

Supplemental Patient Information

• Instruct patients to place the sublingual tablet under the tongue and allow it to completely dissolve; instruct them not to crush, chew, or swallow the tablet whole

Pregnancy Category:NR

Breastfeeding: Safety unknown.

• GI: Transient nausea, gastric disturbance, sublingual irritation (SL tablets)

• Psychotherapeutic agent; exact mechanism of action is unknown; probably acts on neuronal cell metabolism, resulting in improved oxygen uptake and cerebral metabolism, thereby normalizing depressed neurotransmitter levels
• Metabolized in liver
• Excreted in urine
• Half-life: 2.6-5.1 hrs

US Trade Name(s)

• Hydergine

US Availability

ergoloid mesylates (generic)

• TABS: 1 mg
• SL TABS: 0.5 mg

Hydergine

• TABS: 1 mg

Canadian Trade Name(s)

• Hydergine

Canadian Availability

Hydergine

• TABS: 1 mg

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Neurologic

Antidementia Agent

Ergot Alkaloids

Pricing data from www.DrugStore.com in U.S.A.

• Ergoloid Mesylates 1 MG TABS [Bottle] (MAJOR PHARMACEUTICALS)
  30 mg = $85.99
  90 mg = $239.98

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Drug Name: Hydergine 1 MG Oral Tablet

Ingredient(s): Ergoloid mesylates, USP

Imprint: HYDERGINE;1

Color(s): White

Shape: Round

Size (mm): 8.00

Score: 1

Inactive Ingredient(s): lactose / povidone / starch / stearic acid / talc

Drug Label Author:
Novartis Pharmaceuticals Corporation

DEA Schedule:
Non-Scheduled