Adult Dosing

Allergic conjunctivitis

• 1 drop in affected eye(s) up to qid

Pediatric Dosing

• Safety and effectiveness in pediatric patients <3 yrs of age have not been established

Allergic conjunctivitis

• 1 drop in affected eye(s) up to qid

[Outline]

• Adult Dosing
• Pediatric Dosing

• Temporary relief of the signs and symptoms of allergic conjunctivitis

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

• For ophthalmic use only; not for injection or oral use
• To prevent contamination, do not touch the dropper tip to any surface. Keep the container tightly closed
• Instruct the patients not to wear a contact lens if their eye is red
• Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instillation of the drug before they insert their contact lenses

Pregnancy Category:B

Breastfeeding: Absorption from the eye is limited and would not cause any adverse effects to breastfed infants. To diminish the amount of drug that reaches the breastmilk, place pressure over the tear duct by the corner of the eye for 1 min or more and remove the excess solution with an absorbent tissue. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 5 March 2011). Manufacturer advises caution.

• CNS: Headache, abnormal dreams, asthenia
• GI: Bad taste
• EENT: Blurred vision, burning or stinging, corneal infiltrates, corneal staining, dry eye, foreign body sensation, pruritus, keratitis, rhinitis, sinusitis, tearing
• HEMA: Hyperemia
• DERM: Dermatitis
• MISC: Discomfort

• Antihistamine; it selectively antagonizes H1 histamine receptors
• Metabolized in liver; CYP450: unknown
• Excreted in urine 44% (3.6% unchanged)
• Half-life: 3-4 hrs

US Trade Name(s)

• Emadine

US Availability

Emadine

• OPTH SOLN: 0.05%

Canadian Trade Name(s)

• Emadine

Canadian Availability

Emadine

• OPTH SOLN: 0.05%

UK Trade Name(s)

• Emadine

UK Availability

Emadine

• OPTH SOLN: 0.05%

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Ophthalmic

Ophthalmic Antihistamines & Decongestants

Allergy & Immunology

Ophthalmic Antihistamines & Decongestants