Adult Dosing

Tinea cruris, tinea corporis, and tinea versicolor

• Apply to affected areas qd for 2 wks

Cutaneous candidiasis

• Apply to affected areas bid for 2 wks

Tinea pedis ((econazole (generic), Ecoza)

• Apply to affected areas qd for 1 month

Pediatric Dosing

• Safety and effectiveness in pediatric patients have not been established

• Treatment of tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, tinea versicolor (econazole (generic))
• Treatment of interdigital tinea pedis (Ecoza)

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• For external use only, not for ophthalmic use
• Discontinue the therapy, if a reaction suggesting sensitivity or chemical irritation occurs

Pregnancy Category:C

Breastfeeding: Safety unknown. Topical econazole has not been studied during breastfeeding; less than 1% is absorbed after topical application, causes a low risk to the nursing infant. Avoid application to the nipple area and make sure the infant's skin does not come in contact with applied area. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 17 January 2011). Manufacturer advises caution.

• DERM: Burning, itching, stinging, erythema, rash, pruritus

• Antifungal agent; inhibits ergosterol synthesis resulting in increased cellular permeability causing leakage of cellular contents
• Minimal systemic absorption with topical application
• Metabolism: Unknown; CYP450: Unknown
• Renally excreted <1%; feces <1%
• Half-life: Unknown

US Trade Name(s)

• Ecoza

US Availability

econazole (generic)

• CRE: 1%

Ecoza

• AEROSOL FOAM: 1 %

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• Pevaryl

UK Availability

Pevaryl

• CRE: 1%

Australian Trade Name(s)

• Pevaryl

Australian Availability

Pevaryl

• CRE: 1%
• FOAMING SOLN: 1%

Dermatologic

Antifungals (Topical)

Azole Derivatives

Pricing data from www.DrugStore.com in U.S.A.

• Econazole Nitrate 1 % CREA [Tube] (PERRIGO PHARMACEUTICALS)
  85 % = $49.99
  255 % = $133.98

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.