Adult Dosing

Facilitating removal of epiretinal tissue

• Carefully apply 0.15% to the retinal membrane using a blunt cannula, without allowing the cannula to contact or damage the retina
• Perform a [fluid-air exchange’, i.e. filling the entire vitreous cavity with air, to prevent aqueous dilution
• All excess dye should be removed from the vitreous cavity before performing an air-fluid exchange, to prevent unnecessary spreading of the dye
• Intended to be applied directly on the areas where membranes could be present, staining any portion of the membrane which comes in contact with the dye

Pediatric Dosing

Facilitating removal of epiretinal tissue

• Carefully apply 0.15% to the retinal membrane using a blunt cannula, without allowing the cannula to contact or damage the retina

[Outline]

• Adult Dosing
• Pediatric Dosing

• Indicated for use as an aid in ophthalmic surgery by staining the epiretinal membranes during ophthalmic surgical vitrectomy procedures, facilitating removal of the tissue

• Hypersensitivity to any of the ingredients of the product
• Insertion of a non-hydrated (dry state), hydrophilic acrylic intraocular lens (IOL)

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic adjustment: Dose adjustments not defined

• It is recommended that after injection all excess should be immediately removed from the eye
• Should be removed from the eye immediately after staining

Pregnancy Category:C

Breastfeeding: Safety unknown; it is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when trypan blue is administered to a nursing woman

• EENT: Discoloration of high water content hydrogen intraocular lenses, inadvertent staining of the posterior lens capsule and vitreous face

• Ophthalmic aid; selectively stains membranes in the human eye during posterior surgery, such as epiretinal membranes (ERM) and internal limiting membranes (ILM)
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Membraneblue

US Availability

Membraneblue

• OPTH SOLN: 0.15 %

Visionblue

• OPTH SOLN: 0.06 %

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Ophthalmic

Other Ophthalmics