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Use and Dosing

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Hypertension

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:C (1st trimester) and D (2nd and 3rd trimesters)

Breastfeeding: Safety unknown for trandolapril; alternate drug might be preferred, especially while nursing a newborn baby. According to manufacturer's data, trandolapril should not be administered to nursing women. Verapamil is poorly excreted in breast milk; would not be expected to cause any adverse effects in breastfed infants, especially if the infant is >2 months. Verapamil information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT) Verapamil is compatible and considered safe with breastfeeding based upon data from AAP Policy Guidelines (available at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;108/3/776 last accessed 10 December 2010 ). However, manufacturer advices not to administer trandolapril/verapamil to nursing mothers

Adverse Reactions

Clinical Pharmacology

trandolapril

verapamil

Brands and Availability

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US Trade Name(s)

US Availability

trandolapril/verapamil (generic)

Tarka (trandolapril/verapamil)

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Canadian Trade Name(s)

Canadian Availability

Tarka (trandolapril/verapamil

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UK Trade Name(s)

UK Availability

Tarka (trandolapril/verapamil)

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Australian Trade Name(s)

Australian Availability

Tarka (trandolapril/verapamil)

Tarka (trandolapril/verapamil)


[Outline]

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Classification

Cardiovascular

Antihypertensive Combinations

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill