Adult Dosing
Acute musculoskeletal pain
- 1-2 tabs PO qid
- Max dose: 2 tabs qid
Note: Use up to 2-3 wks
Pediatric Dosing
Acute musculoskeletal pain
>16 yrs
- 1-2 tabs PO qid
- Max dose: 2 tabs qid
Note: Use up to 2-3 wks
[Outline]
See Supplemental Patient Information
- On prolonged therapy with carisoprodol cases of dependence, withdrawal, and abuse have occurred; patients having history of addiction can be more susceptible
- Avoid abrupt withdrawal of therapy
- Serious/fatal gastrointestinal (GI) adverse reactions including bleeding, perforation, and obstruction of the stomach, small intestine, or large intestine have occurred due to aspirin
- Use the lowest effective aspirin dose for the shortest possible duration
- Patients without known prior exposure to aspirin are more prone to serious anaphylaxis and anaphylactoid reactions; provide emergency care for such patients
- Gastrointestinal adverse reactions can be induced due to aspirin
- Safety and efficacy in patients with renal or hepatic impairment have not been established
Cautions: Use cautiously in
- Renal impairment
- Hepatic impairment
- History of aspirin-associated GI bleeding
- Ulcers (complicated ulcers)
- Gastritis
- History of PUD
- GERD
- Aspirin-associated ulcers (uncomplicated ulcers)
- Patients taking higher doses of aspirin
- Patients taking concomitant anticoagulants
- Patients using concomitant CNS depressants
- Patients taking NSAIDs
- Patients taking large amounts of alcohol
- History or risk of abuse
- Thrombocytopenia
- Surgery or trauma
- Intracranial lesion
- ICP increased
- History or risk of seizure
- Gout (high-dose ASA)
- Debilitated patients
- Geriatric patients
Supplemental Patient Information
- Advise patients to avoid engaging in activities requiring mental alertness such as operating a hazardous machinery or driving an automobile
- Advise patients to avoid alcoholic beverages and to consult with their clinician before taking other CNS depressants
- Advise patients to contact their healthcare provider if musculoskeletal symptoms persists even after therapy of up to 2-3 wks
- Warn patients that serious GI complications could occur requiring hospitalization; GI complications may also result in death. Instruct patients to remain alert to symptoms of serious GI bleeding such as hematemesis, melena, hematochezia and immediately seek medical attention
- Instruct patients to remain alert to symptoms of an anaphylactoid reaction or anaphylaxis; immediately seek emergency help
Pregnancy Category:D
Breastfeeding: Not necessarily a reason to discontinue breastfeeding if carisoprodol is required by the mother. Slight sedation has occurred in a breastfed newborn infant on exposing carisoprodol during pregnancy and lactation; effect is more pronounced in newborns when exposed for the first time during nursing. Prefer an alternative agent especially while nursing a newborn or preterm infant. Avoid aspirin during breastfeeding, especially with very young infants; although a rare single low dose of aspirin daily is unlikely to cause problems in the infant. The risks with chronic high dose aspirin use are less clear. Monitor infant salicylate serum levels particularly in neonates. Avoid breastfeeding for 1-2 hrs after a dose to minimize antiplatelet effects. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 24 December 2010). Carisoprodol may reduce effective infant feeding (due to sedation) and/or decreased milk production. Nursing mothers should avoid the use of aspirin as it may lead to bleeding in the infant. Manufacturer advises to use the product in a pregnant woman only if clearly needed.
US Trade Name(s)
US Availability
aspirin/carisoprodol (generic)
Soma compound
Canadian Trade Name(s)
Canadian Availability
UK Trade Name(s)
UK Availability
Australian Trade Name(s)
Australian Availability
[Outline]
Pricing data from www.DrugStore.com in U.S.A.
- Soma Compound 200-325 MG TABS [Bottle] (MEDA PHARMACEUTICALS)
30 mg = $139.99
90 mg = $399.96
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.