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Use and Dosing

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Treatment of renal, steroid-resistant cardiac or hepatic allograft rejection

Notes:

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Treatment of acute renal, steroid-resistant cardiac or hepatic allograft rejection

Notes:

[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment:

Hepatic Dose Adjustment:

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:C

Breastfeeding: Safety unknown. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, analyzing the importance of the drug to the mother.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

Orthoclone OKT3

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Canadian Trade Name(s)

Canadian Availability

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UK Trade Name(s)

UK Availability

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Australian Trade Name(s)

Australian Availability

Orthoclone OKT3


[Outline]

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Classification

Allergy & Immunology

Antibodies; Monoclonal (Immunosuppressive)

Gastrointestinal

Antibodies; Monoclonal (Immunosuppressive)

Rheumatologic

Antibodies; Monoclonal (Immunosuppressive)

Neurologic

Antibodies; Monoclonal (Immunosuppressive)