Adult Dosing
Prophylaxis of influenza A (seasonal flu)
- 100 mg PO bid
- Start prior to or immediately upon exposure
Treatment of influenza A (seasonal flu)
- 100 mg PO bid x 7 days
- Start within 48 hours after onset of signs and symptoms of influenza A infection and discontinue within 24-48 hrs of signs and symptoms resolution
Pediatric Dosing
Prophylaxis of influenza A (seasonal flu)
- 1-9 yrs
- 5 mg/kg/day PO; start prior to or immediately upon exposure
- Max: 150 mg/day
- 10-16 yrs
- 100 mg PO bid
- Max: 200 mg/day
- Start prior to or immediately upon exposure
- Note: Safety and effectiveness in pediatric patients of <1 yrs have not been established
[Outline]
Renal Dose Adjustment (Based on CrCl)
- CrCl<10 mL/min: 100 mg PO qd
Hepatic Dose Adjustment
- Severe hepatic impairment: 100 mg PO qd
Elderly nursing home patients
- Elderly nursing home patients: 100 mg PO qd
- An increased incidence of seizures may occur in patients with a history of epilepsy. Discontinue therapy on development of seizures
- The safety and efficacy of this drug has not been evaluated in hepatic insufficiency
- Consider transmission of rimantadine-resistant virus when treating patients whose contacts are at high risk for development of influenza A illness. Resistant Influenza A virus strains may emerge in patients during course of therapy and such resistant strains have been shown to be transmissible and to cause typical influenza illness
- The activity or effectiveness of rimantadine therapy in subjects infected with resistant virus has not been established
- During the course of influenza, serious bacterial infections may begin with influenza-like symptoms or may coexist or may occur as complications
Cautions: Use cautiously in
- Renal insufficiency
- Hepatic insufficiency
- History of seizures
Pregnancy Category:C
Breastfeeding: Possibly unsafe; excreted in the milk of lactating rats and the concentration of rimantadine in milk at 2 to 3 hours following administration is approximately twice than that of serum. Manufacturer advises to avoid using this drug in nursing mothers.
Pricing data from www.DrugStore.com in U.S.A.
- Flumadine 100 MG TABS [Bottle] (CARACO)
14 mg = $43.99
42 mg = $109.97 - Rimantadine HCl 100 MG TABS [Bottle] (GLOBAL PHARMACEUTICAL CORP)
30 mg = $69.99
90 mg = $195.97
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
17 yrs of age
