Adult Dosing

Superficial ocular infections

• Apply directly into conjunctival sac qd-tid
• Acute Infection-Instill 1/4” to 1/2” ribbon into conjunctiva, every 3-4 hours
• Mild-to-moderate infections - Instill 1/4” to 1/2” ribbon into conjunctiva, 2-3 times/day for 7-10 days
• Note: In blepharitis, remove all scales and crusts and apply uniformly over lid margins

Pediatric Dosing

• Safety and effectiveness in pediatric patients have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Short-term topical treatment of superficial ocular infections caused by susceptible bacteria

• Hypersensitivity to bacitracin or any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• Do not use in deep-seated ocular infections or in those infections that are likely to become systemic
• Prolonged use may result in overgrowth of nonsusceptible organisms particularly fungi; institute appropriate therapy if superinfection occurs
• To prevent contamination, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed
• If more than one topical ophthalmic drug is being used, administer at least ten minutes apart

Pregnancy Category:C

Breastfeeding: Safety unknown; poorly excreted in breast milk, considered to pose low risk to the nursing infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 17 August 2010)

• EENT: Blurred vision
• DERM: Photosensitivity

• Polypeptide antibiotic; interferes with bacterial cell wall synthesis
• Minimal systemic absorption after ophthalmic administration
• Not metabolized significantly; CYP450: none
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Only generic available

US Availability

bacitracin (generic)

• OPTH OINT: 500 units/g (3.5 g)

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Antimicrobials

Ophthalmic Anti-infectives

Infectious Disease

Ophthalmic Anti-infectives

Ophthalmic

Ophthalmic Anti-infectives