Adult Dosing

Hyperpigmentation

• Apply cream or solution to the affected area(s) bid

Pediatric Dosing

• Safety and efficacy have not been established in pediatric patients <12 years of age

Hyperpigmentation (>12 yrs)

• Apply cream or solution to the affected area(s) bid

• Hyperpigmentation

• Hypersensitivity to any of the ingredients of the product
• Hypersensitivity to sulfites

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• Do not use on sunburned, abraded skin, over miliaria rubra or on an open wound or after shaving or using depilatory agent
• It can cause contact dermatitis, dryness, erythema, burning and irritation, discontinue the therapy if rash or irritation develops
• Long term use (up to 8 yrs) of 5% hydroquinone creams has been reported to produce ochronosis and colloid milium
• Some commercially available topical formulations of hydroquinone contain sulfites that may cause allergic-type reactions, including anaphylaxis and life-threatening or less severe asthmatic episodes, in certain susceptible individuals

Pregnancy Category:C

Breastfeeding: Safety unknown.

• DERM: Contact dermatitis, dryness, fissuring, erythema, burning, irritation

• Depigmenting Agent; increases the excretion of melanin from melanocytes
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Aclaro
• Aclaro PD
• Alphaquin HP
• Eldopaque Forte
• Eldopaque
• Eldoquin Forte
• Eldoquin
• EpiQuin Micro
• Esoterica Regular
• Lustra AF
• Lustra
• Lustra-Ultra
• Melanex
• Melpaque HP
• Melquin-3
• Melquin-HP
• Nuquin HP
• Palmer's Skin Success Fade Cream
• Solaquin Forte

US Availability

hydroquinone, Alphaquin HP, Eldopaque Forte, Eldoquin Forte, Epiquin Micro, Lustra-AF, Lustra, Lustra-Ultra, Melpaque HP, Melquin HP, Nuquin HP, Solaquin Forte

• CRE: 4%

Eldopaque, Eldoquin, Esoterica Regular, Palmer's Skin Success Fade Cream

• CRE: 2%

Aclaro, Aclaro PD

• Emulsion: 4%

Melanex, Melquin-3

• SOL: 3%

Nuquin HP

• GEL: 4%

Canadian Trade Name(s)

• Active 4
• Clairissime Clear Complexion Lotion
• Clarite 4
• Creme Blanchissante
• Eldopaque
• Eldopaque forte
• Eldoquin
• Eldoquin forte
• Esoterica Regular
• Esoterica unscented
• Lustra
• Palmer’s Skin Success Fade Cream- For Dry skin

Canadian Availability

Active 4, Clarite 4, Eldopaque forte, Eldoquin forte, Lustra

• CRE: 4%

Clairissime Clear Complexion Lotion

• LOTN: 2%

Creme Blanchissante, Eldopaque, Eldoquin, Esoterica Regular, Palmer’s Skin Success Fade Cream- For Dry skin

• CRE: 2%

Esoterica unscented

• CRE: 1.5%

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

Dermatologic

Dermatologic Topical Agents

Depigmenting Agents

Pricing data from www.DrugStore.com in U.S.A.

• Lustra-Ultra 4 % CREA [Tube] (TARO)
  56.8 % = $142.79
  170.4 % = $409.47
• Hydroquinone 4 % CREA [Tube] (PERRIGO PHARMACEUTICALS)
  28.35 % = $29.99
  85.05 % = $69.97
• Melpaque HP 4 % CREA [Tube] (STRATUS PHARMACEUTICALS)
  28.4 % = $33.99
  85.2 % = $93.98
• Nuquin HP 4 % CREA [Tube] (STRATUS PHARMACEUTICALS)
  30 % = $34.99
  90 % = $99.97

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.