Adult Dosing

Head lice infestations

• Apply lotion to dry hair in an amount sufficient (up to 1 tube) to thoroughly coat the hair and scalp
• Rinse off with water after 10 minutes

Note:

• Tube is intended for single use; discard any unused portion

Pediatric Dosing

• Safety has not been established for pediatric patients <6 months of age

Head lice infestations

Children >6 months

• Apply lotion to dry hair in an amount sufficient (up to 1 tube) to thoroughly coat the hair and scalp
• Rinse off with water after 10 minutes

Note:

• Tube is intended for single use; discard any unused portion

[Outline]

• Adult Dosing
• Pediatric Dosing

• Topical treatment of head lice infestations in patients 6 months of age and older

Note:

• Product should be used in the context of an overall lice management program

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Intended for topical use only; not for oral, ophthalmic, or intravaginal use
• Administer only under direct adult supervision to pediatric patients in order to prevent ingestion
• Avoid contact with eyes

Supplemental Patient Information

• Advise patients to apply lotion to dry scalp and dry scalp hair
• Instruct patients to avoid contact with eyes
• Inform patients to use it for single use only and to discard tube after use
• Instruct patients to keep out of reach of children
• Instruct patients to wash hands after applying the lotion

Pregnancy Category:C

Breastfeeding: Limited data indicate that ivermectin is poorly excreted into breastmilk and does not adversely affect the breastfed infants. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 15 February 2012). Manufacturer advises caution.

• EENT: Conjunctivitis, ocular hyperemia, eye irritation
• DERM: Dandruff, dry skin, skin burning sensation

• Pediculicide; binds selectively and with high affinity to glutamate-gated chloride channels in invertebrate nerve and muscle cells, which causes an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the cell leading to paralysis and death of the parasite
• Minimal systemic absorption
• Metabolized by liver
• Half-life: Unknown

US Trade Name(s)

• Sklice

US Availability

Sklice (ivermectin)

• LOTN: 0.5%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Antimicrobials

Antiparasitics, Topical

Dermatologic

Scabicidal Agents