section name header

Interacting Drugs

OBJECT DRUGS

PRECIPITANT DRUGS


Comment:

Patients on ACEI have developed severe hypotension after starting tizanidine therapy. Tizanidine, like the antihypertensive drug clonidine, is an alpha-2 adrenergic agonist, and may have additive hypotensive effects with ACE inhibitors.


Class 3: Assess Risk & Take Action if Necessary