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Use and Dosing

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Symptoms associated with cold, hay fever, or other upper respiratory allergies

Vicks Formula 44 Custom Care Congestion

Note:

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Symptoms associated with cold, hay fever, or other upper respiratory allergies

Children's Sudafed PE Cold & Cough, PediaCare Children's Multi-Symptom Cold

Children's Triaminic Day Time Cold & Cough

Little Colds Decongestant Plus Cough

Vicks Formula 44 Custom Care Congestion

Note:


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:C (dextromethorphan), C (phenylephrine)

Breastfeeding: No studies conducted on the excretion of dextromethorphan in milk or its effect on breastfed infants. However, this medication can be administered to infants as young as 1 month of age. It is unlikely that with usual maternal dose, amounts in milk are as large as those given directly to infants or that breastfed infants would be harmed by the drug in breastmilk, especially in infants over 1 month of age. Avoid the use of products with a high alcohol content while nursing. Phenylephrine is unlikely to reach the infant in large amounts, as the oral bioavailability of phenylephrine is only about 40%. However, oral administration of phenylephrine decreases milk production. As no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 22 July 2011). Manufacturer advises to consult a health professional.

Adverse Reactions

Clinical Pharmacology

Dextromethorphan

Phenylephrine

Brands and Availability

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US Trade Name(s)

US Availability

Children's Sudafed PE Cold & Cough (dextromethorphan/phenylephrine)

Children's Triaminic Day Time Cold & Cough (dextromethorphan/phenylephrine)

Little Colds Decongestant Plus Cough (dextromethorphan/phenylephrine)

PediaCare Children's Multi-Symptom Cold (dextromethorphan/phenylephrine)

Vicks Formula 44 Custom Care Congestion (dextromethorphan/phenylephrine)

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Canadian Trade Name(s)

Canadian Availability

Daytime Cough & Cold (dextromethorphan/phenylephrine)

Little Colds Decongestant Plus Cough (dextromethorphan/phenylephrine)

Neocitran Thin Strips Daytime Cough And Cold (dextromethorphan/phenylephrine)

Triaminic Daytime Cough & Cold (dextromethorphan/phenylephrine)

Triaminic Thin Strips Cold & Cough (dextromethorphan/phenylephrine)

Vicks Custom Care Nasal Congestion/Cough (dextromethorphan/phenylephrine)

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UK Trade Name(s)

UK Availability

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Australian Trade Name(s)

Australian Availability


[Outline]

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Classification

Allergy/Cold

Antitussive, Combinations

ENT

Antitussive, Combinations