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Use and Dosing

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Prevention of NSAID-induced gastric ulcers

Note:

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in:

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:X

Breastfeeding: Misoprostol is a prostaglandin E1 analogue. Prostaglandin E1 and other prostaglandins appear normally in colostrum and milk. Because of the low levels of misoprostol in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. No special precautions are required. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 01 April 2011). According to manufacturer's data, misoprostol is metabolized to misoprostol acid in the mother, which is then excreted in breast milk. There are no adverse events reported of misoprostol in breastfeeding infants of mothers. Use with caution.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

misoprostol (generic)

Cytotec

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Canadian Trade Name(s)

Canadian Availability

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UK Trade Name(s)

UK Availability

Cytotec

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Australian Trade Name(s)

Australian Availability

Cytotec


[Outline]

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Classification

Gastrointestinal

GI Agents; Miscellaneous

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill