Adult Dosing

Impetigo

• Apply a thin layer to affected areas bid x 5 days
• Limit to area < 100 cm²; cover with sterile gauze or bandage

Pediatric Dosing

Impetigo

> 9 months

• Apply a thin layer to affected areas bid x 5 days
• Limit to area < 2% of TBSA; cover with sterile gauze or bandage

<9 months

• Safety and effectiveness have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Impetigo

• Hypersensitivity to any of the ingredients of the product

Renal dose Adjustment

• No dose adjustment

Hepatic dose Adjustment

• No dose adjustment

• If sensitization or severe local irritation occurs, discontinue and wipe off the ointment; administer appropriate alternative therapy
• Not tested for use on mucosal surfaces; topical use only
• Take appropriate measures if superinfection occur during therapy
• Increases the risk of the development of drug-resistant bacteria, if used in the absence of a proven suspected bacterial infection

Pregnancy Category:B

Breastfeeding: Safety is not established; excretion in human milk is unknown. Manufacturer advices caution as many drugs are excreted in human milk.

• CNS: Headache
• DERM: Pruritus, eczema, contact dermatitis, erythema
• EENT: Nasopharyngitis
• GI: Diarrhea, nausea
• LOCAL: Application-site irritation, paresthesia, pain
• MISC: Pyrexia, superinfection

• Pleuromutilin; acts by inhibiting the initiation of protein synthesis at bacterial 50S ribosome
• Liver; extensively metabolized by mono-oxygenation and N-demethylation into various metabolites; CYP450: 3A4 substrate
• Minimal systemic availability after topical application
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Altabax

US Availability

Altabax

• OINT: 1%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• Altargo

UK Availability

Altargo

• OINT: 1%

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Antimicrobials

Dermatologic Topical Agents

Antibiotics

Infectious Disease

Dermatologic Topical Agents

Antibiotics

Dermatologic

Dermatologic Topical Agents

Antibiotics

Pricing data from www.DrugStore.com in U.S.A.

• Altabax 1 % OINT [Tube] (GLAXO SMITH KLINE)
  15 % = $99.99
  45 % = $285.98
• Altabax 1 % OINT [Tube] (GLAXO SMITH KLINE)
  30 % = $181.48
  90 % = $509.2
• Altabax 1 % OINT [Tube] (GLAXO SMITH KLINE)
  5 % = $49.33
  15 % = $127.17

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.