section name header

Use and Dosing

Adult Dosingnavigator.gif

Cold/fever/hay fever or other upper respiratory allergies

Note:

Pediatric Dosingnavigator.gif

Cold/fever/hay fever or other upper respiratory allergies

Theraflu Cold & Sore Throat

Theraflu Flu & Sore Throat

Note:


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:B (acetaminophen), C (pheniramine, phenylephrine)

Breastfeeding: Acetaminophen component of this combination drug is a good choice for analgesia and fever reduction in nursing mothers. Amounts excreted in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.Phenylephrine is unlikely to reach the infant in large amounts, as the oral bioavailability of phenylephrine is only about 40%. However, oral administration of phenylephrine decreases milk production. As no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. This information is based upon Lactmed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 5 Dec 2011). Maternal medication of acetaminophen is usually compatible with breastfeeding; no observable change was seen in the nursing infant while the mother was ingesting the compound. This information is based upon data from AAP Policy Guidelines (available at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;108/3/776/T6 last accessed 10 May 2011). Safety of pheniramine during breastfeeding is unknown. Manufacturer recommends consulting a healthcare professional before using this combination drug in nursing mothers.

Adverse Reactions

Clinical Pharmacology

Acetaminophen

Pheniramine

Phenylephrine

Brands and Availability

flag_usa32.png

US Trade Name(s)

US Availability

Theraflu Cold & Sore Throat (acetaminophen/pheniramine/phenylephrine)

Theraflu Flu & Sore Throat (acetaminophen/pheniramine/phenylephrine)

flag_canada32.png

Canadian Trade Name(s)

Canadian Availability

Extra Strength Neocitran Cold Night, Rhume Et Grippe Extra-Fort (acetaminophen/pheniramine/phenylephrine)

Neocitran Cold Night, Theraflu Cold And Flu (acetaminophen/pheniramine/phenylephrine)

flag_uk32.png

UK Trade Name(s)

UK Availability

flag_australia32.png

Australian Trade Name(s)

Australian Availability


[Outline]

flag_usa32.pngflag_canada32.pngflag_uk32.pngflag_australia32.png

Classification

Allergy/Cold

Antitussive, Combinations

ENT

Antitussive, Combinations