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Interacting Drugs

OBJECT DRUGS

Anticoagulants, Oral:

PRECIPITANT DRUGS

Absorption Inhibitors:


Comment:

Bile acid binding resins and sucralfate bind with warfarin, phenprocoumon, and possibly other oral anticoagulants in the G.I. tract, thus reducing the anticoagulant absorption and response. Since warfarin and phenprocoumon undergo enterohepatic circulation, the binding cannot be completely avoided by spacing doses of the drugs.


Class 3: Assess Risk & Take Action if Necessary