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Use and Dosing

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Hypertension

Note:

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on Crcl)

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:D

Breastfeeding: Safety unknown; Prefer an alternative drug during breastfeeding as appropriate literature on the use of amlodipine is unavailable. As low levels of benazepril are excreted in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse reactions in breastfed infants. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 9 December 2010). Small amounts of unchanged benazepril and benazeprilat are excreted into the breast milk of lactating women, so a newborn child ingesting breast milk would receive <0.1% of the maternal doses. Unknown whether the amlodipine is excreted in human milk. Manufacturer advises to discontinue nursing or therapy.

Adverse Reactions

Clinical Pharmacology

Amlodipine

Benazepril

Brands and Availability

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US Trade Name(s)

US Availability

amlodipine/benazepril (generic)

Lotrel (amlodipine/benazepril)

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Canadian Trade Name(s)

Canadian Availability

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UK Trade Name(s)

UK Availability

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Australian Trade Name(s)

Australian Availability


[Outline]

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Classification

Cardiovascular

Antihypertensive Combinations

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill