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Use and Dosing

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Initial therapy

Replacement or add on therapy

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use cautiously in

Pregnancy/Breast Feeding

Pregnancy Category:D

Breastfeeding: Safety unknown. Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production. Valsartan: No data available for the use of valsartan during breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 20 May 2011). Hydrochlorothiazide maternal medication usually compatible with breastfeeding, no observable change was seen in the nursing infant while the mother was ingesting the compound. This information is based upon data from AAP Policy Guidelines (available at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;108/3/776/T6 last accessed 20 May 2011). Due to the potential for serious adverse reactions in nursing infants, manufacturer recommends discontinuation of nursing or discontinuation of drug, taking into account the importance of the drug to the mother.

Adverse Reactions

Clinical Pharmacology

hydrochlorothiazide

valsartan

Brands and Availability

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US Trade Name(s)

US Availability

hydrochlorothiazide/valsartan (generic)

Diovan HCT (hydrochlorothiazide/valsartan)

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Canadian Trade Name(s)

Canadian Availability

hydrochlorothiazide/valsartan (generic)

Diovan HCT (hydrochlorothiazide/valsartan)

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UK Trade Name(s)

UK Availability

Co-Diovan

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Australian Trade Name(s)

Australian Availability

Co-Diovan


[Outline]

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Classification

Cardiovascular

Antihypertensive Combinations

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill