Postoperative Opioid depression
- Give doses in increments of 0.1-0.2 mg IV, q2-3 min until the desired response. Repeat 1-2 hrs or 0.005 mg/kg IV repeated in 15 min
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Therapy is for intramuscular or subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
Opioid overdose (known or suspected)
- 0.4-2 mg IV. Repeat after 2-3 mins if required. (Max total: 10 mg)
- When IV is not available, IM or SC route may be used
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Use for intramuscular and subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
Emergency therapy in settings where opioids may be present
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Therapy is for intramuscular or subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
Opioid Overdose–Known or Suspected
- The usual initial dose in children is 0.01 mg/kg body weight given I.V. If this dose does not result in the desired degree of clinical improvement, a subsequent dose of 0.1 mg/kg body weight may be administered. If an I.V. route of administration is not available, naloxone may be administered I.M. or S.C. in divided doses.
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Therapy is for intramuscular or subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
- Caregiver should pinch the thigh muscle while administering the dose
Postoperative Opioid depression
- Give doses in increments of 0.005-0.01 mg IV q2-3 mins until the desired response
Neonatal Opioid-induced Depression
- The usual initial dose is 0.01 mg/kg body weight administered I.V., I.M. or S.C. This dose may be repeated in accordance with adult administration guidelines for postoperative opioid depression.
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Therapy is for intramuscular or subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
- Caregiver should pinch the thigh muscle while administering the dose
Emergency therapy in settings where opioids may be present
- Upon actuation, Evzio automatically inserts the needle IM/SC 0.4 mg , and retracts the needle fully into its housing
Note:
- Therapy is for intramuscular or subcutaneous use only
- Administer drug into the anterolateral aspect of the thigh, through clothing if necessary
- Additional doses may be administered every 2-3 minutes until emergency medical assistance arrives
- Caregiver should pinch the thigh muscle while administering the dose
