Adult Dosing
Actinic keratoses of the face or scalp
- Apply 20% soln to the individual lesion (scalp/face) q8 wks, followed 14-18 hrs later by blue light illumination using the BLU-U Blue Light Photodynamic Therapy Illuminator
Note:
- To be applied by qualified medical personnel
- Do not apply on scalp or face lesions simultaneously
Pediatric Dosing
- Safety and effectiveness in pediatric patients has not been established
[Outline]
See Supplemental Patient Information
- After application of aminolevulinic acid topical solution and prior to blue light treatment, do not expose the treatment sites to sunlight or bright indoor light as the treatment site will become photosensitive and can result in a stinging and/or burning sensation erythema and/or edema of the lesions
- Aminolevulinic acid topical solution should be used by a qualified health professional only and to be applied to actinic keratoses lesion and not perilesional skin, as it may become photosensitized skin and may produce a stinging and/or burning sensation and may become erythematous and/or edematous upon exposure to blue light treatment
- If for any reason the patient cannot return for blue light treatment during the prescribed period after application of aminolevulinic acid topical solution, patient should be advised to avoid exposure of the photosensitized lesions to sunlight or prolonged or intense light for at least 40 hours
- Aminolevulinic acid topical solution can cause excessive irritation if applied under occlusion, do not apply to the eyes or to mucous membranes
- Safety of aminolevulinic acid topical solution has not been evaluated in patients with inherited or acquired coagulation defects
Caution: Use cautiously in
- Inherited or acquired coagulation defects
Supplemental Patient Information
- Advise patients to avoid exposure to sunlight or bright indoor light after application of the topical solution
Pregnancy Category:C
Breastfeeding: Safety unknown, the levels of ALA or its metabolites have not been measured in the milk, as many drugs are excreted in human milk, manufacturer advises caution while administered to a nursing woman.
