See Supplemental Patient Information
- Systemic symptoms of atropine poisoning have occurred on excessive use in patients having a history of susceptibility to belladonna alkaloids; discontinue medication and use appropriate therapy
- Avoid use in infants due to association between the cycloplegia and the development of amblyopia
- Feeding intolerance has occurred in neonates; withhold feeding for 4 hrs after examination
- Avoid use in concentrations >0.5% in small infants
- Compress the lacrimal sac by digital pressure for 2-3 minutes after instillation to avoid excessive systemic absorption
- Precipitation of acute angle closure glaucoma has occurred in susceptible individuals and in those with shallow anterior chambers
- Determine IOP and depth of angle of anterior chamber before treatment to decrease risk of inducing glaucoma
- For infants under 3 months, eye ointment is preferred due to risk of systemic events with eye drops. Ointment may cause eye irritation, redness and swelling of the eyelids
- Prolonged dilatation has occurred in individuals with Down's syndrome
Cautions: Use cautiously in:
- Infants/small children (increased sensitivity to adverse events)
- Elderly patients (increased sensitivity to adverse events
- Down's syndrome
- Brain damage
- Sensitivity to bright light
- Spastic paralysis
Supplemental Patient Information
- Advise patients to avoid touching dropper tip to any surface as this may contaminate the contents
- Advise patients to avoid driving or engaging in hazardous activities while pupils are dilated
- Advise patients to avoid wearing UV blocking sunglasses during bright light (due to photosensitivity)
Pregnancy Category:C
Breastfeeding: Literature unavailable on the use of atropine during breastfeeding. Prolonged use of an atropine might reduce milk production/letdown, but a ophthalmic dose is unlikely to interfere with breastfeeding. During prolonged use, observe for signs of decreased lactation such as insatiety, poor weight gain (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 23 December 2010). Unknown whether excreted in human milk. Manufacturer advises caution.
Pricing data from www.DrugStore.com in U.S.A.
- Atropine Sulfate 1 % SOLN [Bottle] (BAUSCH & LOMB)
15 % = $101.27
30 % = $168.75 - Isopto Atropine 1 % SOLN [Bottle] (ALCON VISION)
5 % = $39.19
15 % = $93.62 - Atropine Sulfate 1 % SOLN [Bottle] (BAUSCH & LOMB)
5 % = $23.99
15 % = $69.97
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
