Adult Dosing

Relief of pain and itching

Dermoplast, Little Ouchies Pain Relieving Spray

• Apply bid-tid PRN
• Max: qid

Pediatric Dosing

Relief of pain and itching

Dermoplast, Little Ouchies Pain Relieving Spray

• Children >2 yrs
• Apply bid-tid PRN
• Max: qid

[Outline]

• Adult Dosing
• Pediatric Dosing

• Temporary relief of pain and itching associated with sunburn, insect bites, scabies, minor cuts, minor burns, and minor skin irritations

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Avoid contact with leather, fabric and upholstery to prevent possible staining or discoloration
• Indicated for external use only
• Avoid contact with the eyes, mouth and mucus membranes
• Avoid using this combination drug in patients with a history of allergy to local anesthetics such as procaine, butacaine, benzocaine, or any other caine anesthetics
• Avoid application of excessive amounts of this drug on broken, blistered, abraded skin or open wounds and over large surface areas
• Advise patients to avoid spraying this drug on the face or in the mouth and to avoid inhalation
• Fatalities can occur on accidental inhalation of this drug
• Avoid exceeding recommended dosage
• Instruct patients to inform their clinician if they are pregnant or breast feeding
• Keep out of reach of children. On overdosage, seek medical help or contact a Poison Control Center right away
• Discontinue use and immediately consult a physician on worsening of condition, persistence of symptoms >7 days, or if it clears up and occurs again within a few days

Cautions: Use cautiously in

• Hepatic impairment
• Asthma or COPD
• Chronic bronchitis
• Cardiovascular disease
• CNS disease
• Emphysema
• Elderly patients
• Hemoglobin-M disease
• Diabetes mellitus
• Pyruvate-kinase deficiency
• NADH methemoglobin reductase deficiency
• Shock
• G6PD deficiency
• Smoking
• Thyroid disorder
• Patients <2 yrs
• Debilitated patients

Supplemental Patient Information

• Instruct patients to keep the product away from fire, open flame, and heat
• Advise patients not to puncture or incinerate the product
• Instruct patients to avoid smoking during therapy

Pregnancy Category:NR

Breastfeeding: Safety unknown. Topical benzocaine has not been evaluated during breastfeeding, but is unlikely to adversely affect the breastfed infant if it is applied away from the breast. Avoid application to the breast or nipple area as the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 12 August 2011).

• HEMA: Methemoglobinemia
• DERM: Rash, irritation, erythema, local irritation
• MISC: Pain, hypersensitivity reactions

Benzocaine

• Local anesthetic; decreases neuronal membrane permeability to sodium ions by reversibly stabilizing the neuronal membrane, thereby blocking the initiation and conduction of nerve impulses
• Minimal systemic absorption
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

Menthol

• Counterirritant; stimulates cold-sensitive TRPM8 receptors in the skin by inhibiting Ca++ currents of neuronal membranes, thus producing a cooling sensation
• Minimal systemic absorption
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Dermoplast
• Little Ouchies Pain Relieving Spray

US Availability

Dermoplast, Little Ouchies Pain Relieving Spray (benzocaine/menthol)

• OTC SPRAY: 20%/0.5%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Anesthesia

Topical Local Anesthetic/Counterirritant; Combinations