Adult Dosing

Relief of redness

• Instill 1-2 drops in the affected eye(s) qid PRN

Pediatric Dosing

• Safety and effectiveness in pediatric patients <6 yrs of age have not been established

Relief of redness

• 6 yrs: Instill 1-2 drops in the affected eye(s) qid PRN

[Outline]

• Adult Dosing
• Pediatric Dosing

• Relief of redness of the eye due to minor eye irritations

• Hypersensitivity to any of the ingredients of the product
• Angle-closure glaucoma

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• Avoid touching the eyelids or surrounding areas with the dropper tip as this could contaminate the medication resulting in serious ocular infections
• Patients should remove contact lenses before using eye drops
• Contraindicated in patients with narrow-angle glaucoma
• Overuse may cause more eye redness
• Discontinue use and consult a physician if the redness or irritation of the eye worsens or persists for more than 72 hours, or if the patient feels eye pain and/or changes in vision

Cautions: Use cautiously in

• Hypertension
• CV disease
• Hyperglycemia (diabetes)
• Hyperthyroidism

Pregnancy Category:C

Breastfeeding: No information is available on the use of oxymetazoline during breastfeeding. Because of local administration and limited absorption into the maternal bloodstream, very less amount of drug reaches the infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 19 April 2011).

• EENT: Increased IOP, rebound conjunctival hyperemia, transient blurred vision, transient occular stinging

• Ophthalmic decongestant (sympathomimetic); reduces ocular congestion and redness by stimulating alpha adrenergic receptors
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Ocuclear
• Visine L.R.

US Availability

Ocuclear, Visine L.R.

• OTC OPTH SOLN: 0.025%

Canadian Trade Name(s)

• Claritin Eye Allergy Relief
• Visine Workplace

Canadian Availability

Claritin Eye Allergy Relief

• OTC OPTH DROPS: 0.25 mg/mL

Visine Workplace

• OTC OPTH DROPS: 0.025%

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Ophthalmic

Ophthalmic Decongestants

Alpha Adrenergic Agonists