See Supplemental Patient Information
- Avoid administration during acute gastrointestinal illness
- Avoid concomitant use in patients treated with sulfonamides and antibiotics as it may prevent to induce a protective immune response
- On persistent diarrhea or vomiting postpone vaccination
- Follow a complete immunization schedule to obtain an optimum immune response
- Vaccination with typhoid vaccine does not ensure complete protection against typhoid fever, travelers should take all necessary precautions to avoid contact or ingestion of potentially contaminated food or water
- Take utmost care for safe and effective use of vaccine
- Ask about the recent health status of the patient to be immunized prior to administration of vaccine; obtain immunization history of the patient and current antibiotic usage
- Use of the antimalarial drug proguanil (not available in U.S.) should only be given after 10 days since final dose of live typhoid vaccine.
Supplemental Patient Information
- Inform patients/caregivers about the benefits and risks of immunization with vaccine
- Advise to take necessary precautions to avoid contact with or ingestion of contaminated food and water
- Instruct patients to swallow capsules approximately 1 hour before a meal with a cold or luke-warm (temperature should be < body temperature
- Advise patients to swallow as soon as capsule is placed in the mouth. Instruct to avoid chewing the capsule
- Inform patients about the necessity of taking all 4 capsules in the correct schedule, and the importance of proper storage temperature of the capsules
Pregnancy Category:C
Breastfeeding: The Centers for Disease Control and Prevention states that vaccines given to a nursing mother does not affect breastfed infants and breastfeeding is not a contraindication to typhoid vaccine. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 20 December 2010). Unknown whether excreted in human milk. Manufacturer advises to use only if the vaccine is of utmost need as no literature is available to warrant the use of this product in nursing mothers for passive antibody transfer to an infant.
2 yrs of age
