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Interacting Drugs

OBJECT DRUGS

Antipsychotics, Atypical:

PRECIPITANT DRUGS

Enzyme Inducers:


Comment:

These antipsychotics are metabolized by CYP3A4; drugs that induce CYP3A4 may reduce their serum levels resulting in loss of efficacy. For example, carbamazepine may reduce olanzapine concentrations by about 50%.


Class 3: Assess Risk & Take Action if Necessary