Adult Dosing

Superficial ocular infections

• Apply 1 cm ribbon into lower conjunctival or infected structure up to 6 times/day x 7-10 days, depending on severity of infection

Pediatric Dosing

Superficial ocular infections

• Apply 1 cm ribbon into lower conjunctival sac or infected structure up to 6 times/day x 7-10 days, depending on severity of infection

Ophthalmia neonatorum; prophylaxis

• Instill 1 cm ribbon of ointment into the lower conjunctival sac of each eye

[Outline]

• Adult Dosing
• Pediatric Dosing

• Treatment of superficial ocular infections caused by strains of susceptible organism
• Prophylaxis of ophthalmia neonatorum

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic dose adjustment

• Hepatic impairment: No dose adjustments

• Overgrowth of non-susceptible organisms including fungi may occur with use of antimicrobial agents, stop administration and institute appropriate therapy
• To prevent contamination, do not touch the container tip to any surface, including the eye
• Use new tube for each infant and don't flush after instillation
• It can cause mild ocular irritations, redness and hypersensitivity reactions

Pregnancy Category:B

Breastfeeding: Probably safe. Minimal systemic absorption; maternal use of ophthalmic erythromycin is unlikely to affect the breastfed infant. Monitor the infant for irritability and possible effects on the gastrointestinal flora. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 17 February 2011). Manufacturer advises caution.

• EENT: Ocular irritation, redness
• MISC: Hypersensitivity reactions

• Macrolide; inhibits protein synthesis by binding 50S ribosomal subunits of susceptible organisms
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Only generic available

US Availability

erythromycin (generic)

• OINT: 5 mg/g

Canadian Trade Name(s)

• Ak Mycin
• Diomycin
• Onguent ophtalmique D'erythromycine

Canadian Availability

erythromycin (generic)

• OINT: 5 mg/g

Ak Mycin

• OINT: 5 mg/g

Diomycin

• OINT: 5 mg/g

Onguent ophtalmique D'erythromycine

• OINT: 5 mg/g

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Ophthalmic

Ophthalmic Anti-infectives

Macrolides

Infectious Disease

Ophthalmic Anti-infectives

Macrolides