Adult Dosing

Surgical hand scrub

• Apply 5 mL onto wet hands and forearms and rub into a copious lather by adding small amounts of water; scrub well with a wet brush for 3 minutes
• Rinse thoroughly with running water and dry
• For repeat surgical scrubs during the day, scrub thoroughly with the same amount for 3 minutes; rinse thoroughly with water and dry

Bacteriostatic cleansing

• Dispense 5 mL onto wet palm, work up a lather with water and apply to area to be cleansed; rinse thoroughly after each washing

Pediatric Dosing

Surgical hand scrub

• Apply 5 mL onto wet hands and forearms and rub into copious lather by adding small amounts of water; scrub well with a wet brush for 3 minutes
• Rinse thoroughly with running water and dry

Bacteriostatic cleansing

• Dispense 5 mL onto wet palm, work up a lather with water and apply to area to be cleansed; rinse thoroughly after each washing

• Should not be used routinely for bathing infants
• In premature infants, baby skin products containing alcohol may decrease the antibacterial action of this drug

• Indicated for use as a surgical scrub and a bacteriostatic skin cleanser
• Used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful

• Hypersensitivity to any of the ingredients of the product
• Burned or denuded skin
• As an occlusive dressing, wetpack, or lotion
• Routinely for prophylactic total body bathing
• Routinely for bathing infants
• Patients with primary light sensitivity to halogenated phenol derivatives
• As a vaginal pack or tampon or on any mucous membranes

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Rapid absorption may occur with resultant toxic blood levels of the drug when applied to skin lesions such as ichthyosis congenita, dermatitis of Letterer-Siwe's syndrome, or other generalized dermatological conditions. Application to burns may produce neurotoxicity and death
• Infants, especially premature infants or those with dermatoses are more susceptible to hexachlorophene absorption
• Promptly discontinue therapy on occurrence of signs/symptoms of cerebral irritability
• Incidence of dermatitis, irritability, generalized clonic muscular contractions, and decerebrate rigidity have developed in infants following application of 6% hexachlorophene powder
• Avoid contact with eyes; if accidental contact occurs, rinse with water immediately
• Rinse thoroughly after each use, particularly in sensitive areas such as scrotum and perineum
• Do not pour into measuring cups, medicine bottles, or similar containers as it may be mistaken for baby formula or other medications

Caution: Use cautiously in

• Burns

Supplemental Patient Information

• Advise patients not to use this product on burned/denuded areas, as an occlusive dressing/wetpack/lotion, routinely for prophylactic total body bathing, as a vaginal pack, or on any mucous membranes, on persons with sensitivity to any of its components or who have demonstrated primary light sensitivity to halogenated phenol derivatives, or routinely for bathing infants
• Advise patients to discontinue therapy and contact a physician if irritation, sensitization, or allergic reactions occur during therapy

Pregnancy Category:C

Breastfeeding: As per manufacturer's data, because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, analyzing the importance of the drug to the mother.

• CNS: Cerebral irritability and convulsions (premature infants)
• DERM: Dermatitis, photosensitivity, redness, mild scaling/dryness
• MUSC: Generalized clonic muscular contractions, decerebrate rigidity (premature infants)

• Anti-infective agent; exhibits bacteriostatic action against staphylococci and other gram-positive bacteria by inhibiting the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase
• Minimal systemic absorption
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Phisohex
• Pre-Op
• Pre-Op II

US Availability

Phisohex

• EMUL: 3%

Pre-Op, Pre-Op II

• SPONGE: 480 mg

Canadian Trade Name(s)

• Phisohex

Canadian Availability

Phisohex

• EMUL: 3%

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• Only generic available

Australian Availability

hexachlorophane (generic)

• LOTN: 3%

Antimicrobials

Antiseptics & Germicides

Infectious Disease

Antiseptics & Germicides

Dermatologic

Antiseptics & Germicides

Pricing data from www.DrugStore.com in U.S.A.

• Phisohex 3 % LIQD [Bottle] (SANOFI-AVENTIS U.S.)
  473 % = $55.99
  1419 % = $165.98
• Phisohex 3 % LIQD [Bottle] (SANOFI-AVENTIS U.S.)
  148 % = $35.99
  444 % = $85.97

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.