Adult Dosing

• 10ml solution=89mg elemental calcium=2.2mmols=4.4mEq

Hypocalcemia

• 7-14 mEq IV q1-3 days depending on the patient’s response

Hypocalcemic tetany

• 4.5-16 mEq IV using 10% calcium gluconate until therapeutic response occurs
• Max: 15 g of calcium gluconate (67.5 mEq calcium ion)

Severe hyperkalaemia

• 4.5-9.0 mEq IV as an adjunct, repeated as required under ECG control

Hypermagnesaemia

• 7 mEq IV

Calcium Channel Blocker Overdose [Non-FDA Approved]

• 60ml IV bolus dose (over 5-10 min) followed by continuous infusion of 0.6 to 1.2 ml/kg per hour

Pediatric Dosing

• 10ml solution=89mg elemental calcium=2.2mmols=4.4mEq

Hypocalcemia

• 1-7 mEq IV q1-3 days depending on the patient’s response

Hypocalcemic tetany

• Children: 0.5-0.7 mEq/kg IV q6-8 hrs or until tetany is controlled
• Neonates: 2.4 mEq/kg/day IV in divided doses

Calcium Channel Blocker Overdose [Non-FDA Approved]

• 0.6ml/kg (60 mg/kg) bolus dose followed by continuous infusion of 0.6 to 1.2 ml/kg per hour

[Outline]

• Adult Dosing
• Pediatric Dosing

• Hypocalcemic tetany
• Hypocalcemia related to hypoparathyroidism
• Hypocalcemia caused by rapid growth or pregnancy
• Hyperkalemia-induced cardiac toxicity (if not receiving digitalis)
• Treatment of Black widow spider bites to relieve muscle cramping
• Adjunctive treatment of rickets
• Adjunctive treatment of osteomalacia
• Adjunctive treatment of lead colic
• Adjunctive treatment of magnesium sulfate overdosage
• To decrease capillary permeability in allergic conditions, nonthrombocytopenic purpura, and exudative dermatoses

• Hypersensitivity to any of the ingredients of the product
• Ventricular fibrillation
• Hypercalcemia
• Digitalis toxicity

• N/A

Renal Dose Adjustment

• Renal impairment: Caution advised, dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

• For intravenous use only, do not use for Subcutaneous or intramuscular injection as it may cause severe necrosis and sloughing
• Calcium gluconte injection contains aluminum, prolonged parenteral administration in impaired kidney function and in premature neonates, accumulate aluminum at levels associated with central nervous system and bone toxicity
• Calcium gluconate should be administered slowly into a large vein to avoid too rapid increase in serum calcium and extravasation of calcium solution into the surrounding tissue with resultant necrosis
• Vasodilation, decreased blood pressure, bradycardia, cardiac arrhythmias, syncope and cardiac arrest occurs with rapid calcium gluconate infusion
• Concomitant use of calcium salts and drugs of the digitalis group is fatal, avoid intravenous injection of a calcium compound in digitalized patient unless indications are clearly defined

Cautions: Use cautiously in

• Renal impairment
• Cardiovascular disease
• History of renal calculi
• Sarcoidosis
• Hyperparathyroidism
• Hypercalciuria

Pregnancy Category:C

Breastfeeding: Safety unknown, it is not known whether this drug is excreted in breast milk. However, manufacturer advises caution when administered to a nursing woman.

• CV: Vasodilation, hypotension, bradycardia, cardiac arrhythmias, syncope and cardiac arrest
• DERM: Tingling sensations
• GI: Chalky taste, constipation, nausea
• METABOLIC: Hypercalcemia
• GU: Renal calculi
• LOCAL: Extravasation necrosis, abscess
• MISC: Hot flushes

• Mineral supplement; maintains cell membrane and capillary permeability, assists transmission of nerve impulses and contraction of cardiac, skeletal, and smooth muscle, activator in many enzymatic reactions, essential for coagulation, regulates release of hormones, helps uptake of amino acid and cyanocobalamin
• Metabolism: Infused calcium becomes part of body calcium pool

US Trade Name(s)

• Only generic available

US Availability

Calcium gluconate (generic)

• INJ: 10%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• Only generic available

UK Availability

Calcium gluconate (generic)

• INJ: 10%

Australian Trade Name(s)

• Only generic available

Australian Availability

Calcium gluconate (generic)

• INJ: 10% (10, 50 ml vials)

[Outline]

Nutrition/Electrolytes

Minerals & Electrolytes