Adult Dosing
Anxiety
Alcohol withdrawal; symptomatic relief
- Start 10 mg PO tid-qid x 1 day; then 5 mg PO tid-qid PRN
Muscle spasm/ spasticity due to CP
Seizure disorder, adjunct therapy
Tetanus [Non-FDA Approved]
Vertigo [Non-FDA Approved]
Pediatric Dosing
Anxiety
- Child (>6 mo): 1-2.5 mg PO tid-qid; gradually increase as tolerated and needed
Muscle spasm/ spasticity due to CP
- Child (>6 mo): 1-2.5 mg PO tid-qid; gradually increase as tolerated and needed
Seizure disorder, adjunct therapy
- Child (>6 mo): 1-2.5 mg PO tid-qid; gradually increase as tolerated and needed
Tetanus [Non-FDA Approved]
- 0.04 to 0.2 mg/kg/dose PO q2-4h; Max 10 mg/dose
[Outline]
- Usage of tranquilizers (diazepam, meprobamate and chlordiazepoxide) during the first trimester of pregnancy is associated with an increased risk of congenital malformations in the neonates. Avoid use during this period
- It is not intended for use in patients with primary depressive disorder, psychosis, or disorders in which anxiety is not prominent
- Safety and effectiveness in pediatric patients below the age of 6 months have not been established. Prolonged central nervous system depression has been observed in neonates
- Use cautiously in the elderly, may accumulate and lead to psychomotor impairment
- Withdrawal syndrome has occurred within 4 to 6 wks of treatment, especially if abruptly discontinued. Taper dose gradually to discontinue
- Monitor CBC, LFTs if prolonged therapy
Cautions: Use cautiously in
- Renal impairment
- Hepatic impairment
- CNS depressant use
- Impaired pulmonary function
- Psychosis
- Suicidal ideation
- Alcohol abuse
- Substance abuse
Pregnancy Category:D
Breastfeeding: Safety unknown. Due to long half-life of diazepam and nordiazepam, timing breastfeeding with respect to the dose would be of little benefit in reducing infant exposure. Other agents should be preferred, especially while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 3 November 2009).
US Trade Name(s)
US Availability
diazepam (generic)
- TABS: 2, 5, 10 mg
- SOLN: 5 mg/5 mL
- CONC: 5 mg/mL
Valium
Canadian Trade Name(s)
Canadian Availability
diazepam (generic)
- TABS: 2, 5, 10 mg
- SOLN: 1 mg/mL
Valium
Vivol
UK Trade Name(s)
UK Availability
diazepam (generic)
- TABS: 2, 5, 10 mg
- SOLN: 2 mg/5 mL (50, 100, 150, 250, 300, 500 mL)
- SOLN: 5 mg/5 mL (50, 100, 150, 250, 300, 500 mL)
Australian Trade Name(s)
- Antenex
- Ducene
- Ranzepam
- Valium
- Valpam
Australian Availability
diazepam (generic)
- TABS: 2, 5 mg
- ELIXIR: 10 mg/10 mL (100 mL)
Antenex, Ducene, Valium, Valpam
Ranzepam
[Outline]
Pricing data from www.DrugStore.com in U.S.A.
- Valium 10 MG TABS [Bottle] (ROCHE)
30 mg = $195.98
90 mg = $560.99 - Diazepam 5 MG TABS [Bottle] (MYLAN)
30 mg = $11.99
60 mg = $13.98 - Diazepam 1 MG/ML SOLN [Bottle] (ROXANE)
60 ml = $15.99
120 ml = $21.97 - Diazepam Intensol 5 MG/ML CONC [Bottle] (ROXANE)
30 ml = $32.99
90 ml = $79.97 - Valium 5 MG TABS [Bottle] (ROCHE)
30 mg = $115.99
90 mg = $322.98 - Valium 2 MG TABS [Bottle] (ROCHE)
30 mg = $74.99
90 mg = $219.98
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
