Adult Dosing

Superficial infections of the external auditory

• Insert a cotton wick saturated with acetic acid into the ear canal; the wick may be saturated after insertion; instruct the patient to keep the wick in for 24 hrs and to keep it moist by adding 3-5 drops of solution q4-6 hrs
• May remove the wick after 24 hrs but the patient should continue to instill 5 gtt of solution tid-qid daily thereafter, for as long necessary

• Prior to initiation of therapy, remove all cerumen and debris to allow for direct contact of acetic acid with infected surfaces

Pediatric Dosing

• Safety and effectiveness in pediatric patients <3 yrs of age have not been established

Superficial infections of the external auditory

• Insert a cotton wick saturated with acetic acid into the ear canal; the wick may be saturated after insertion; keep the wick inside the ear canal for 24 hrs and keep it moist by adding 3-4 gtt of solution every q4-6 hrs
• May remove the wick after 24 hrs but continue to instill 3-4 gtt tid or qid thereafter, for as long necessary

Note:

• Prior to initiation of therapy, remove all cerumen and debris to allow for direct contact of acetic acid with infected surfaces

[Outline]

• Adult Dosing
• Pediatric Dosing

• Treatment of superficial infections of the external auditory canal

• Hypersensitivity to any of the ingredients of the product
• Herpes simplex infection
• Vaccinia and varicella
• Perforated tympanic membrane

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

• Promptly discontinue therapy if sensitization or irritation occurs
• Transient stinging or burning may sometimes be experienced when the drug is first instilled into the acutely inflamed ear

Pregnancy Category:B

Breastfeeding: Safety unknown. Topical hydrocortisone has not been studied during breastfeeding. Short-term application is unlikely to pose a risk to the breastfed infant by passage into breast milk. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 20 June 2011).

• EENT: Stinging, burning, local irritation

Acetic acid

• Antibacterial and antifungal; acidifies ear canal and exerts astringent, bactericidal, and fungicidal effects
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

Hydrocortisone

• Anti-inflammatory; suppresses inflammation and the normal immune response
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Acetasol HC

US Availability

Acetasol HC [acetic acid/hydrocortisone] (generic)

• SOLN: 2%/1%

Vosol HC (acetic acid/hydrocortisone)

• SOLN: 2%/1%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Antimicrobials

Otic Steroids With Anti-infectives

Infectious Disease

Otic Steroids With Anti-infectives

ENT

Otic Steroids With Anti-infectives

Pricing data from www.DrugStore.com in U.S.A.

• Acetasol HC 2-1 % SOLN [Bottle] (ACTAVIS MID ATLANTIC)
  10 % = $220
  30 % = $609.97

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.